Unicentric Castleman Disease and Pheochromocytoma
  • Rosana Maia
    Department of Medicine, Unidade Local de Saúde do Alto Minho, Viana do Castelo, Portugal
  • Joana Couto
    Department of Medicine, Unidade Local de Saúde do Alto Minho, Viana do Castelo, Portugal
  • José Diogo Martins
    Department of Medicine, Unidade Local de Saúde do Alto Minho, Viana do Castelo, Portugal
  • Edgar Torre
    Department of Medicine, Unidade Local de Saúde do Alto Minho, Viana do Castelo, Portugal
  • Diana Guerra
    Department of Medicine, Unidade Local de Saúde do Alto Minho, Viana do Castelo, Portugal

Keywords

IL-6, adenomegaly, adrenal mass, pheochromocytoma, Castleman disease

Abstract

Castleman disease is an uncommon and heterogenous lymphoproliferative disorder which is classified as unicentric or multicentric depending on the number of lymph nodes involved. Each type has a different clinical presentation, aetiology, treatment and prognosis. We report the case of a young woman who presented with cervical lymphadenopathy and a retroperitoneal mass, and was diagnosed with unicentric Castleman disease and pheochromocytoma. We describe the diagnostic steps, the complications that developed, and the importance of the differential diagnosis in the evaluation of these patients.

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References

  • Fajgenbaum DC, Shilling D. Castleman disease pathogenesis. Hematol Oncol Clin North Am 2018;32:11–21. doi: 10.1016/j.hoc.2017.09.002.
  • Carrion DM, Alvarez-Maestro M, Gómez Rivas J, Brygadyr Y, García-Fernandez E, Martínez-Piñeiro L. Challenging diagnosis of a solitary retroperitoneal mass: a case report of Castleman’s disease and review of the literature. Urol Int 2019;103(2):245–248. doi: 10.1159/000493511.
  • Wong RSM. Unicentric Castleman disease. Hematol Oncol Clin North Am 2018;32(1):65–73. doi: 10.1016/j.hoc.2017.09.006.
  • Ciacciarelli M. IL-6-producing, noncatecholamines secreting pheochromocytoma presenting as fever of unknown origin. Case Rep Med 2016;2016:3489046. doi: 10.1155/2016/3489046.
  • Nishimura MF, Nishimura Y, Nishikori A, Maekawa Y, Maehama K, Yoshino T, et al. Clinical and pathological characteristics of hyaline-vascular type unicentric Castleman disease: a 20-year retrospective analysis. Diagnostics 2021;11:2008.

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    Published: 2022-01-14
    Issue: 2022: Vol 9 No 1 (view)

    How to cite:
    1.
    Maia R, Couto J, Martins JD, Torre E, Guerra D. Unicentric Castleman Disease and Pheochromocytoma. EJCRIM 2022;9 doi:10.12890/2022_003068.

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