Refractory Orbital Myositis in Systemic Lupus Erythematosus - A Role for Rituximab

  • Joana Rodrigues Morais Internal Medicine Department, Hospital Pedro Hispano, Unidade Local de Saúde de Matosinhos, Portugal https://orcid.org/0000-0003-3717-4488
  • Raquel Rodrigues Santos Internal Medicine Department, Hospital Pedro Hispano, Unidade Local de Saúde de Matosinhos, Portugal
  • Paula Pires Costa Internal Medicine Service, Hospital do Divino Espírito Santo, Ponta Delgada, Portugal
  • Tomás Fonseca Clinical Immunology Unit, Centro Hospitalar Universitário do Porto, Portugal
  • Fátima Farinha Clinical Immunology Unit, Centro Hospitalar Universitário do Porto, Portugal

Keywords

Orbital myositis, systemic lupus erythematosus, corticosteroids, rituximab

Abstract

Orbital myositis in systemic lupus erythematosus (SLE) is a rare entity with risk of serious complications. Timely treatment with effective immunosuppressors is desirable.

We report a case of a 32-year-old female patient with SLE who presented with an acute ocular pain and extraorbital muscle thickening, consistent with orbital myositis.

Association with SLE was made after exclusion of other aetiologies. Due to refractoriness to steroids, off-label rituximab was initiated with clinical and imaging parameter improvement.

VIEW THE ENTIRE ARTICLE

References

  • Serop S, Vianna RNG, Claeys M, De Laey JJ. Orbital myositis secondary to systemic lupus erythematosus. Acta Ophthalmol 1994;72(4):520–523.
  • Silpa-archa S, Lee JJ, Foster CS. Ocular manifestations in systemic lupus erythematosus. Br J Ophthalmol 2016;100:135–141.
  • Chan AJ, Rai AS, Lake S. Orbital myositis in systemic lupus erythematosus: a case report and literature review. Eur J Rheumatol 2020;7(3):135–137.
  • Palejwala NV, Walia HS, Yeh S. Ocular manifestations of systemic lupus erythematosus: a review of the literature. Autoimmune Dis 2012;2012:290898.
  • Espinoza GM. Orbital inflammatory pseudotumors: etiology, differential diagnosis, and management. Curr Rheumatol Rep 2010;12:443–447
  • Published: 2021-12-10

    Issue: 2021: Vol 8 No 12 (view)

    Section: Articles

    How to cite:
    1.
    Rodrigues Morais J, Rodrigues Santos R, Pires Costa P, Fonseca T, Farinha F. Refractory Orbital Myositis in Systemic Lupus Erythematosus - A Role for Rituximab. EJCRIM 2021;8 doi:10.12890/2021_003038.

    Most read articles by the same author(s)