The Development of Ecchymosis after Administration of Convalescent Serum in a Patient with COVID-19 Associated with Thrombocytosis

  • Rajashree Khot Department of General Medicine, AIIMS, Nagpur, Maharashtra, India
  • Sunita Kumbhalkar Department of General Medicine, AIIMS, Nagpur, Maharashtra, India
  • Richa Juneja Department of Pathology (Haematology), AIIMS, Nagpur, Maharashtra, India
  • Prashant P Joshi Department of General Medicine, AIIMS, Nagpur, Maharashtra, India

Keywords

COVID-19, thrombocytosis, convalescent plasma reaction, ecchymoses

Abstract

COVID-19 can have an unpredictable and severe course, leading to many hypotheses regarding its pathophysiology and clinical manifestations. Haematological manifestations are a significant predictor of disease severity. The most common observation is lymphopenia with an increased neutrophil:lymphocyte ratio. Platelets have been implicated in thrombogenic events, but the most frequently reported abnormality is mild thrombocytopenia.<br />
Here we present an interesting case of a patient with moderate COVID-19 who presented with cutaneous ecchymoses and thrombocytosis, and discuss this paradox.

Author Biographies

Sunita Kumbhalkar ,
Department of General Medicine, AIIMS, Nagpur, Maharashtra, India

Professor

Dept of General Medicine

All India Institute of Medical Sciences

Nagpur

Richa Juneja ,
Department of Pathology (Haematology), AIIMS, Nagpur, Maharashtra, India

Assistant Professor (Haematology)

Dept of Pathology

All India Institute of Medical Sciences

Nagpur

Prashant P Joshi ,
Department of General Medicine, AIIMS, Nagpur, Maharashtra, India

Professor

Dept of General Medicine

All India Institute of Medical Sciences

Nagpur

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References

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  • Published: 2021-10-08

    Issue: 2021: Vol 8 No 9 (view)

    Section: Articles

    How to cite:
    1.
    Khot R, Kumbhalkar S, Juneja R, Joshi PP. The Development of Ecchymosis after Administration of Convalescent Serum in a Patient with COVID-19 Associated with Thrombocytosis. EJCRIM 2021;8 doi:10.12890/2021_002782.