Cardiac Arrest and Inverted Takotsubo Cardiomyopathy Following Intramyometrial Vasopressin Injection During Myomectomy

  • Alenka Golicnik Department for Intensive Internal Medicine, University Medical Center Ljubljana, Slovenia
  • Eda Vrtacnik Bokal Department for Reproduction, University Medical Center Ljubljana, Slovenia
  • Vojka Gorjup Department for Intensive Internal Medicine, University Medical Center Ljubljana, Slovenia

Keywords

Inverse Takotsubo cardiomyopathy, vasopressin, myomectomy

Abstract

Vasopressin is involved in cardiovascular homeostasis that can influence coronary perfusion. It is commonly used as a local vasoconstricting agent during gynaecological procedures.

We present a case of cardiac arrest and inverse Takotsubo features following intramyometrial vasopressin administration during myomectomy. The patient was successfully resuscitated and recovered completely. Cardiac presentation was compatible with inverse Takotsubo cardiomyopathy that could have been triggered by high-dose vasopressin-induced coronary vasoconstriction. The patient’s cardiac function resolved with no long-term sequelae.

Takotsubo cardiomyopathy usually results from an excessive catecholaminergic surge. High-dose vasopressin-induced coronary vasospasm could have been the mechanism underlying the clinical presentation in our patient.

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  • Published: 2021-05-21

    Issue: 2021: Vol 8 No 5 (view)

    Section: Articles

    How to cite:
    1.
    Golicnik A, Vrtacnik Bokal E, Gorjup V. Cardiac Arrest and Inverted Takotsubo Cardiomyopathy Following Intramyometrial Vasopressin Injection During Myomectomy. EJCRIM 2021;8 doi:10.12890/2021_002504.