Investigating Febrile Polyserositis: An Unusual Case of Idiopathic Hypereosinophilic Syndrome
  • Inês Rueff Rato
    Internal Medicine Department, Centro Hospitalar de Vila Nova de Gaia/Espinho, Porto, Portugal
  • Joana Rigor
    Internal Medicine Department, Centro Hospitalar de Vila Nova de Gaia/Espinho, Porto, Portugal
  • Paula Ferreira
    Internal Medicine Department, Centro Hospitalar de Vila Nova de Gaia/Espinho, Porto, Portugal
  • Joana Laranjinha
    Infectious Diseases, Hospital Pedro Hispano, Porto, Portugal
  • Gualter Santos Silva
    Cardiology Department, Centro Hospitalar de Vila Nova de Gaia/Espinho, Porto, Portugal
  • Daniela Martins-Mendes
    nternal Medicine Department, Centro Hospitalar de Vila Nova de Gaia/Espinho, Porto, Portugal; Biomedicine Department, Faculty of Medicine of Porto University, Porto, Portugal; i3S - Institute for Research and Innovation of Porto University, Porto, Portugal

Keywords

Hypereosinophilic syndrome, polyserositis, eosinophilic alveolitis, eosinophilic pleurisy, eosinophilic pericarditis

Abstract

Hypereosinophilic syndrome (HES) is a heterogenous group of diseases characterized by abnormal accumulation of eosinophils in the blood or peripheral tissues. It can affect all organs and therefore clinical manifestations are highly variable. We describe the case of a 38-year-old man admitted for febrile polyserositis. He developed cardiac tamponade requiring pericardiocentesis complicated by left ventricle perforation which was successfully repaired. He presented mild peripheral eosinophilia. Bronchoalveolar lavage evidenced eosinophilic alveolitis, and pleural and pericardium histopathology revealed the presence of abundant eosinophils. All other causes of tissue eosinophilia were excluded and the diagnosis of idiopathic HES was made. The patient was started on glucocorticoids with resolution of symptoms. This case report describes a rare but potentially fatal presentation of HES and demonstrates the difficulty and delay in diagnosis when peripheral hypereosinophilia is absent.

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    Published: 2021-04-02
    Issue: 2021: Vol 8 No 4 (view)


    How to cite:
    1.
    Rueff Rato I, Rigor J, Ferreira P, Laranjinha J, Santos Silva G, Martins-Mendes D. Investigating Febrile Polyserositis: An Unusual Case of Idiopathic Hypereosinophilic Syndrome. EJCRIM 2021;8 doi:10.12890/2021_002426.

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