Chronic Copper Sulfate Poisoning
  • Ana Paula Perestrelo
    Centro Hospitalar Universitário Cova da Beira, Alameda Pêro da Covilhã, Covilhã, Portugal
  • Gonçalo Filipe Lopes Miranda
    Centro Hospitalar Universitário Cova da Beira http://orcid.org/0000-0002-5011-0940
  • Maria Inês Gonçalves
    Centro Hospitalar Universitário Cova da Beira, Alameda Pêro da Covilhã, Covilhã, Portugal
  • Carolina Belino
    Centro Hospitalar Universitário Cova da Beira, Alameda Pêro da Covilhã, Covilhã, Portugal
  • Rosa Ballesteros
    Centro Hospitalar Universitário Cova da Beira, Alameda Pêro da Covilhã, Covilhã, Portugal

Keywords

Copper sulfate poisoning, kidney injury

Abstract

Copper, as a salt, is toxic and has the potential to harm multiple organs. Copper intoxication causes intravascular haemolysis followed by liver and kidney failure that can be fatal. We present a case of chronic copper sulfate poisoning in a 66-year-old man with dysphagia to solids and liquids, anaemia, acute kidney injury, liver cytolysis and hypocalcaemia. The patient improved with supportive care, but chronic kidney disease was established. Anamnesis was crucial for the diagnosis, given the non-specific signs and symptoms. The history of chronic exposure to pest treatment with a blue dust cloud made us suspect copper sulfate poisoning.

VIEW THE ENTIRE ARTICLE

References

  • Arena M, Auteri D, Barmaz S, Bellisai G, Brancato A, Brocca D, et al. Peer review of the pesticide risk assessment of the active substance copper compounds copper(I), copper(II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper(I) oxide, Bordeaux mixture. EFSA J 2018;16(1):e05152.
  • Gunay N, Yildirim C, Karcioglu O, Gunay NE, Yilmaz M, Usalan C, et al. A series of patients in the emergency department diagnosed with copper poisoning: recognition equals treatment. Tohoku J Exp Med 2006;209(3):243–248.
  • Gamakaranage CS, Rodrigo C, Weerasinghe S, Gnanathasan A, Puvanaraj V, Fernando H. Complications and management of acute copper sulphate poisoning; a case discussion. J Occup Med Toxicol 2011;6(1):34.
  • Yang CC, Wu ML, Deng JF. Prolonged hemolysis and methemoglobinemia following organic copper fungicide ingestion. Vet Hum Toxicol 2004;46(6):321–323.
  • Faure A, Mathon L, Poupelin JC, Allaouchiche B, Chassard, D. Acute cupric sulfate intoxication: pathophysiology and therapy about a case report. Ann Fr Anesth Reanim 2003;22(6):557–559.
  • Franchitto N, Gandia-Mailly P, Georges B, Galinier A, Telmon N, Ducassé JL, et al. Acute copper sulphate poisoning: a case report and literature review. Resuscitation 2008;78(1):92–96.
  • Naha K, Saravu K, Shastry BA. Blue vitriol poisoning: a 10-year experience in a tertiary care hospital. Clin Toxicol 2012;50(3):197–201.
  • Views: 958
    HTML downloads: 87
    PDF downloads: 516


    Published: 2021-02-17
    Issue: 2021: Vol 8 No 2 (view)


    How to cite:
    1.
    Perestrelo AP, Miranda GFL, Gonçalves MI, Belino C, Ballesteros R. Chronic Copper Sulfate Poisoning. EJCRIM 2021;8 doi:10.12890/2021_002309.