Beware of Drug Interactions Treating Iatrogenic Mycobacterium bovis Endocarditis from Intravesical BCG Instillation

  • Francesca Curri Department of Experimental and Clinical Medical Sciences, Clinica Medica, University Hospital, University of Udine, Udine, Italy
  • Andrea Da Porto Department of Experimental and Clinical Medical Sciences, Clinica Medica, University Hospital, University of Udine, Udine, Italy
  • Viviana Casarsa Department of Experimental and Clinical Medical Sciences, Clinica Medica, University Hospital, University of Udine, Udine, Italy
  • Daria Albini Department of Experimental and Clinical Medical Sciences, Clinica Medica, University Hospital, University of Udine, Udine, Italy
  • Giorgio Minen Department of Cardiac Sciences, Cardiology, University Hospital, University of Udine, Udine, Italy
  • Leonardo Alberto Sechi Department of Experimental and Clinical Medical Sciences, Clinica Medica, University Hospital, University of Udine, Udine, Italy

Keywords

BCG, infective endocarditis, disseminated mycobacterial disease

Abstract

We report a case of mechanical mitral valve endocarditis associated with miliary disseminated bacillus Calmette-Guerin (BCG) infection following intravesical instillations for minimally invasive bladder cancer in a 65-year-old man. The diagnosis was established by echocardiographic evidence of vegetation on the prosthetic mitral valve, miliary lesions in the lungs and evidence of bloodstream infection sustained by Mycobacterium. We successfully treated the patient with the classical regimen of quadruple antituberculous therapy.

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  • Published: 2021-03-10

    Issue: Vol 8 No 2 (view)

    Section: Articles

    How to cite:
    1.
    Curri F, Da Porto A, Casarsa V, Albini D, Minen G, Sechi LA. Beware of Drug Interactions Treating Iatrogenic Mycobacterium bovis Endocarditis from Intravesical BCG Instillation. EJCRIM 2021;8 doi:10.12890/2021_002263.