Mesalazine-induced Hypersensitivity Pneumonitis
KeywordsMesalazine, ulcerative colitis, drug reaction, hypersensitivity pneumonitis, lung injury
A 57-year-old woman with Crohn's disease (ulcerative proctitis) treated with mesalazine (5-ASA) developed worsening respiratory distress and cough. The lack of response to antibiotics and the results of bronchoalveolar lavage led to the diagnosis of mesalazine-related hypersensitivity pneumonitis, an infrequent entity. Symptoms improved after discontinuation of mesalazine and the administration of corticosteroid therapy. The authors discuss the diagnosis and management of this rare condition.
Issue: Vol 8 No 1 (view)