Is There More to This Case than Mere Pulmonary Alveolar Proteinosis? A Clinical Case Presentation
  • Tal Frenkel-Rutenberg
    Internal Medicine T, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel
  • Amir Dagan
    Internal Medicine T, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel
  • Eyal Lotan
    Internal Medicine T, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel
  • Dor Lotan
    Internal Medicine "T", Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
  • Gad Segal
    Internal Medicine "T", Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.

Keywords

Pulmonary alveolar proteinosis, GATA2, miscarriage, myelodysplasia syndrome, surfactant

Abstract

Introduction: Pulmonary alveolar proteinosis (PAP) is a rare disease, associated with excess accumulation of surfactant proteins and lipids in the alveoli.

Clinical presentation: We report the case of a 46-year-old woman with a combined presentation of PAP, myelodysplasia and recurrent miscarriages.

Conclusions: The concomitant presentation of the above might be compatible with a mutation of the haematopoietic transcription factor gene GATA2.

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References

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    Published: 2015-06-29
    Issue: Vol. 2 No. 3 (2015) (view)

    How to cite:
    1.
    Frenkel-Rutenberg T, Dagan A, Lotan E, Lotan D, Segal G. Is There More to This Case than Mere Pulmonary Alveolar Proteinosis? A Clinical Case Presentation. EJCRIM 2015;2 doi:10.12890/2015_000210.