Eosinophilic Fasciitis: an Atypical Presentation of a Rare Disease

  • Sabrina Poradosu Department of Internal Medicine Vrij Universitair Ziekenhuis Brussel (Free University Hospital Brussels) Laarbeeklaan 101, 1090 Brussels
  • Esther Vanderlinden Department of Pathology Algemeen Stedelijk Ziekenhuis Aalst Merestraat 80, 9300 Aalst
  • Alex Michotte Department of Neurology and Pathology (Neuropathology), Universitair Ziekenhuis Brussel Laarbeeklaan 101, 1090 Brussels
  • Hendrik De Raeve Department of Pathology Universitair Ziekenhuis Brussel Laarbeeklaan 101, 1090 Brussels
  • Sabine D Allard Department of Internal Medicine, Universitair Ziekenhuis Brussel, Belgium Laarbeeklaan 101, 1090 Brussels

Abstract

Objectives: We report an atypical presentation of eosinophilic fasciitis and provide a concise overview of the literature.

Materials and Methods: Clinical and laboratory findings in a patient presenting with fever and skin induration were recorded. A deep muscle biopsy was performed in order to confirm the diagnosis.

Results: A spontaneous favourable clinical and radiological evolution was observed.

Conclusion: The diagnosis of eosinophilic fasciitis is challenging due to the lack of pathognomonic signs and symptoms. As spontaneous resolution has been described, watchful waiting is defendable depending on the clinical presentation. Although magnetic resonance imaging (MRI) can be useful in establishing the diagnosis, a deep muscle biopsy remains the gold standard diagnostic tool.

VIEW THE ENTIRE ARTICLE

References

  • Pinal-Fernandez I, Selva-O'Callaghan A, Grau JM. Diagnosis and classification of eosinophilic fasciitis. Autoimmun Rev 2014;13:379–382.
  • Shulman LE. Diffuse fasciitis with eosinophilia: a new syndrome? Trans Assoc Am Physicians 1975;88:70–86.
  • Nair PS, Nanda KG, Jayapalan S. The "sign of groove", a new cutaneous sign of internal malignancy. Indian J Dermatol Venereol Leprol 2007;73:141.
  • Guillevin L, Meyer O, Sibilia J. Traité des Maladies et Syndromes Systémiques, 5th ed. Parijs. Médecine Sciences Publications, 2008.
  • Ronneberger MR, Janka R, Schett G, Manger B. Can MRI substitute for biopsy in eosinophilic fasciitis? Ann Rheum Dis 2009;68:1651–1652.
  • Helfgott SM, Varga J. Eosinophilic fasciitis. UpToDate. Wolters Kluwer. http://www.uptodate.com/contents/eosinophilic-fasciitis?source=search_result&search=eosinophilic+fasciitis&selectedTitle=1%7E21. Last accessed 01/12/2014.
  • Boin F, Hummers LK. Scleroderma-like fibrosing disorders. Rheum Dis Clin North Am 2008;34:199–220.
  • Islam MN, Islam MA, Abdal SJ, Azad MAK, Ahmedullah AK, Haq SA. Eosinophilic fasciitis: what matters in management in a developing country—a case report with two and a half-year follow-up. J Health Popul Nutr 2012;30:117–120.
  • Figure 1

    Published: 2015-04-03

    Issue: Vol. 2 No. 2 (2015) (view)

    Section: Articles

    How to cite:
    1.
    Poradosu S, Vanderlinden E, Michotte A, De Raeve H, Allard SD. Eosinophilic Fasciitis: an Atypical Presentation of a Rare Disease. EJCRIM 2015;2 doi:10.12890/2015_000186.

    Similar Articles

    You may also start an advanced similarity search for this article.

    Most read articles by the same author(s)