Isolated Non-Resolving Vulvar Lesion as a Presentation of Disseminated Histoplasmosis in a Woman with HIV

  • Moni Roy Department of Internal Medicine, University of Illinois College of Medicine, OSF Saint Francis Medical Center, Peoria, Illinois, USA
  • Ashish Kumar Roy Department of Internal Medicine, University of Illinois College of Medicine, OSF Saint Francis Medical Center, Peoria, Illinois, USA
  • Jan Nalinee Upalakalin Department of Pathology, OSF Saint Francis Medical Center, Peoria, Illinois, USA
  • Sharjeel Ahmad Department of Internal Medicine, Section of Infectious Diseases, University of Illinois College of Medicine, Peoria, Illinois, USA

Keywords

Disseminated histoplasmosis, vulvar lesion, HIV, AIDS

Abstract

Disseminated histoplasmosis is most commonly caused by Histoplasma capsulatum and is a known opportunistic infection in immunocompromised patients. The clinical presentation of histoplasmosis varies from asymptomatic to a progressive disseminated form. Pulmonary and CNS involvement is common in disseminated histoplasmosis. Rarely, disseminated disease can present as vulvar lesion in the absence of pulmonary symptoms, causing a delay in diagnosis. As per our PubMed literature search, there have only been two reported cases where vulvar lesion was the only presenting symptom of disseminated disease. In our patient, a histopathological diagnosis was made with staining showing budding yeast forms of histoplasma.

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  • Published: 2020-07-16

    Issue: Vol 7 No 10 (view)

    Section: Articles

    How to cite:
    1.
    Roy M, Roy AK, Upalakalin JN, Ahmad S. Isolated Non-Resolving Vulvar Lesion as a Presentation of Disseminated Histoplasmosis in a Woman with HIV. EJCRIM 2020;7 doi:10.12890/2020_001814.