Transcranial Direct Current Stimulation in the Treatment of Subacute Post-Stroke Thalamic Aphasia

  • William Campanella IRCCS Ospedale Policlinico San Martino, Genoa, Italy; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Genoa, Italy
  • Riccardo Pedrini IRCCS Ospedale Policlinico San Martino of Genoa; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Italy
  • Lucilla Vestito IRCCS Ospedale Policlinico San Martino, Genoa, Italy
  • Lucio Marinelli IRCCS Ospedale Policlinico San Martino, Genoa, Italy; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Genoa, Italy
  • Carlo Trompetto IRCCS Ospedale Policlinico San Martino, Genoa, Italy; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Genoa, Italy
  • Laura Mori IRCCS Ospedale Policlinico San Martino, Genoa, Italy; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Genoa, Italy

Keywords

Transcranial direct current stimulation, aphasia, cerebral haemorrhage, speech therapy, rehabilitation

Abstract

Background: Although many studies have demonstrated the effectiveness of transcranial direct current stimulation (tDCS) in improving speech recovery in post-stroke aphasia, as far as we know patients affected by thalamic aphasia have never been investigated.

Patient and method: A 65-year-old man with severe non-fluent aphasia due to a left thalamic haemorrhagic stroke underwent intensive daily speech therapy combined with tDCS. 

Results: The patient showed progressive improvement with almost complete recovery of his speech disorder, behavioural disinhibition and apathy. 
Conclusions: Our findings suggest that tDCS with concurrent speech therapy can be useful in patients with subcortical stroke lesions.

VIEW THE ENTIRE ARTICLE

References

  • Polanía R, Paulus W, Nitsche MA. Modulating cortico-striatal and thalamo-cortical functional connectivity with transcranial direct current stimulation. Hum Brain Mapp 2012;33(10):2499–2508.
  • Ford AA, Triplett W, Sudhyadhom A, Gullett J, McGregor K, Fitzgerald DB, et al. Broca’s area and its striatal and thalamic connections: a diffusion-MRI tractography study. Front Neuroanat 2013;7:8.
  • Llano DA. Functional imaging of the thalamus in language. Brain Lang 2013;126(1):62–72.
  • Biou E, Cassoudesalle H, Cogné M, Sibon I, De Gabory I, Dehail P, et al. Transcranial direct current stimulation in post-stroke aphasia rehabilitation: a systematic review. Ann Phys Rehabil Med 2019;62(2):104–121.
  • Coleman ER, Moudgal R, Lang K, Hyacinth HI, Awosika OO, Kissela BM, et al. Early rehabilitation after stroke: a narrative review. Curr Atheroscler Rep 2017;19(12):59.
  • Pavlova EL, Semenov RV, Guekht AB. Effect of tDCS on fine motor control of patients in subacute and chronic post-stroke stages. J Mot Behav 2020;52(4):383–395.
  • Published: 2020-09-03

    Issue: Vol 7 No 11 (view)

    Section: Articles

    How to cite:
    1.
    Campanella W, Pedrini R, Vestito L, Marinelli L, Trompetto C, Mori L. Transcranial Direct Current Stimulation in the Treatment of Subacute Post-Stroke Thalamic Aphasia. EJCRIM 2020;7 doi:10.12890/2020_001794.

    Most read articles by the same author(s)