Subungual Squamous Cell Carcinoma in a Patient with Psoriasis
  • Sherif Monib
    General Surgery Department, West Hertfordshire Hospitals NHS Trust, St Albans, UK
  • Kevin Seebah
    West General Surgery Department, West Hertfordshire Hospitals NHS Trust, St Albans, UK

Keywords

Subungual squamous cell carcinoma, psoriasis, PUVA, cyclosporine

Abstract

Subungual squamous cell carcinoma (SCC) is a rare malignant tumour with an indolent course and unknown aetiology. It is usually misdiagnosed as a benign lesion, resulting in delayed treatment. Although psoriasis is not a precancerous skin condition, the treatment modalities cyclosporine and psoralen with ultraviolet A (PUVA) might increase the risk of developing cutaneous SCC, although a relationship has not been confirmed.
We describe a patient with psoriasis who had been treated with cyclosporine and PUVA 6 years previously. He developed back SCC 2 years later, a subungual skin lesion after another 2 years and presented to us 1 year later, when nail elevation and biopsy revealed SCC.

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    Published: 2020-07-13
    Issue: 2020: Vol 7 No 10 (view)

    How to cite:
    1.
    Monib S, Seebah K. Subungual Squamous Cell Carcinoma in a Patient with Psoriasis. EJCRIM 2020;7 doi:10.12890/2020_001788.