COVID-19 in a Patient with Chronic Lymphocytic Leukaemia with Pseudohypoxemia

  • Orivaldo Alves Barbosa Hospital Geral Dr. César Cals, Fortaleza /Ceará, Brazil; Department of Medicine, Christus University Center (UNICHRISTUS), Fortaleza /Ceará, Brazil
  • Talita Guimarães Andrade Department of Medicine, Christus University Center (UNICHRISTUS), Fortaleza /Ceará, Brazil
  • Maria Danielly de Almeida Sousa Department of Medicine, Christus University Center (UNICHRISTUS), Fortaleza /Ceará, Brazil
  • José Walter Correia Department of Internal Medicine, Hospital Geral Dr. César Cals, Fortaleza /Ceará, Brazil

Keywords

Chronic lymphocytic leukaemia, COVID-19, coronavirus, pseudohypoxemia, sepsis

Abstract

Infection with SARS-CoV-2 causes critical disease in approximately 5% of affected patients, particularly the elderly, hypertensive, obese and immunocompromised. Patients with haematological cancer, including chronic lymphocytic leukaemia (CLL), are particularly at risk of complications. Very rarely, patients with extreme leukocytosis may develop spurious hypoxemia, or pseudohypoxemia, which confuses the diagnosis of complications and can lead to intervention errors. We report the case of a patient with CLL, severe infection with SARS-CoV-2 and pseudohypoxemia.

VIEW THE ENTIRE ARTICLE

References

  • Wang C, Horby PW, Hayden FG, Gao GF. A novel coronavirus outbreak of global health concern. Lancet 2020;395(10223):470–473.

  • He W, Chen L, Yuan G, Fang Y, Chen W, Wu D, et al. COVID-19 in persons with haematological cancers. Leukemia 2020;34:1637–1645.

  • Jin X-H, Zheng KI, Pan K-H, Xie Y-P, Zheng M-H. COVID-19 in a patient with chronic lymphocytic leukaemia. Lancet Haematol 2020;7(4):e351–e352.

  • Melchardt T, Weiss L, Greil R, Egle A. Viral infections and their management in patients with chronic lymphocytic leukemia. Leuk Lymphoma 2013;54(8):1602–1613.

  • Perini GF, Fischer T, Gaiolla RD, Rocha TB, Bellesso M, Teixeira LLC, et al. How to manage lymphoid malignancies during novel 2019 coronavirus (CoVid-19) outbreak: a Brazilian task force recommendation. Hematol Transfus Cell Ther 2020;42(2):103–110.

  • Horr S, Roberson R, Hollingsworth JW. Pseudohypoxemia in a patient with chronic lymphocytic leukemia. Respir Care 2013;58(3):e31–e33.

  • Van de Louw A, Desai RJ, Schneider CW, Claxton DF. Hypoxemia during extreme hyperleukocytosis: how spurious? Respir Care 2016;61(1):8.
  • Published: 2020-06-11

    Issue: Vol 7 No 7 (view)

    Section: Articles

    How to cite:
    1.
    Alves Barbosa O, Guimarães Andrade T, de Almeida Sousa MD, Correia JW. COVID-19 in a Patient with Chronic Lymphocytic Leukaemia with Pseudohypoxemia. EJCRIM 2020;7 doi:10.12890/2020_001763.