A Fatal Case of Ciprofloxacin-induced Fulminant Hepatitis

  • Alice V Bevan Department of Gastroenterology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham General Hospital, Cheltenham, UK
  • Duncan J Napier Department of Gastroenterology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham General Hospital, Cheltenham, UK
  • Alexandra Di Mambro Department of Gastroenterology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham General Hospital, Cheltenham, UK

Keywords

Ciprofloxacin, hepatitis, adverse drug reaction

Abstract

Fatal hepatotoxicity associated with ciprofloxacin is extremely rare. This is the second fully investigated case of fulminant hepatotoxicity due to ciprofloxacin in a male patient previously ciprofloxacin tolerant. The patient’s medical history included stable Waldenstrom’s macroglobulinaemia, inguinal hernia repair, prostate cancer (radiotherapy in 2006) and idiopathic Parkinson’s disease. Extensive investigation for progressive liver failure confirmed drug-induced liver injury.

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  • Published: 2020-06-12

    Issue: Vol 7 No 9 (view)

    Section: Articles

    How to cite:
    1.
    Bevan AV, Napier DJ, Di Mambro A. A Fatal Case of Ciprofloxacin-induced Fulminant Hepatitis. EJCRIM 2020;7 doi:10.12890/2020_001612.