Exuberant Hand-Foot-Mouth Disease: An Immunocompetent Adult with Atypical Findings
  • Joana Cordeiro e Cunha
    Internal Medicine Department, Centro Hospitalar do Médio Ave, Vila Nova de Famalicão, Portugal
  • Ana Lima Silva
    Internal Medicine Department, Centro Hospitalar do Médio Ave, Vila Nova de Famalicão, Portugal
  • Renato Maia Nogueira
    Internal Medicine Department, Centro Hospitalar do Médio Ave, Vila Nova de Famalicão, Portugal
  • Diana Silva Fernandes
    Internal Medicine Department, Centro Hospitalar do Médio Ave, Vila Nova de Famalicão, Portugal
  • Tatiana Salazar
    Internal Medicine Department, Centro Hospitalar do Médio Ave, Vila Nova de Famalicão, Portugal
  • Maria Vilela
    Internal Medicine Department, Centro Hospitalar do Médio Ave, Vila Nova de Famalicão, Portugal
  • Jorge Salomão
    Internal Medicine Department, Centro Hospitalar do Médio Ave, Vila Nova de Famalicão, Portugal

Keywords

Hand-foot-mouth disease, enterovirus, viral illness, exanthematous fever

Abstract

Non-polio enteroviruses are ubiquitous viruses responsible for a wide spectrum of disease in people of all ages, although infection and illness disproportionately affect infants and young children. Hand-foot-mouth disease (HFMD) is an enteroviral clinical syndrome most frequently caused by coxsackievirus-A16 and enterovirus-A71. Since 2008, a novel coxsackievirus-A6 genotype has been associated with more severe HFMD in both children and adults, presenting with a unique constellation of findings, and whose prevalence has been increasing over the last few years. In this case report, an atypical clinical picture of confirmed enterovirus HFMD is described in an immunocompetent adult, with exuberant clinical findings, clinically consistent with coxsackievirus-A6 infection. This case report highlights the importance of awareness of the clinical presentation of this increasingly common infection in adults.

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References

  • Romero JR. Introduction to the human enteroviruses and parechoviruses. In: Bennett JE, Dolin R, Blaser MJ, editors. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Philadelphia: Elsevier; 2020, p. 2214–2215.

  • Romero JR. Enteroviruses. In: Goldman L, Schafer AI, editors. Goldman-Cecil Medicine. Philadelphia: Elsevier; 2020, p. 2205–2206.

  • Romero JR. Coxsackieviruses, echoviruses, and numbered enteroviruses (EV-A71, EVD-68, EVD-70). In: Bennett JE, Dolin R, Blaser MJ, editors. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Philadelphia: Elsevier; 2020, p. 2229–2230.

  • Kimmis BD, Downing C, Tyring S. Hand-foot-and-mouth disease caused by coxsackievirus A6 on the rise. Cutis 2018;102(5):353–356.

  • Hubiche T, Schuffenecker I, Boralevi F, Léauté-Labrèze C, Bornebusch L, Chiaverini C, et al. Dermatological spectrum of hand, foot and mouth disease from classical to generalized exanthema. Pediatr Infect Dis J 2014;33(4):e92–e98.
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    Published: 2020-04-13
    Issue: 2020: Vol 7 No 7 (view)


    How to cite:
    1.
    Cordeiro e Cunha J, Silva AL, Nogueira RM, Fernandes DS, Salazar T, Vilela M, Salomão J. Exuberant Hand-Foot-Mouth Disease: An Immunocompetent Adult with Atypical Findings. EJCRIM 2020;7 doi:10.12890/2020_001609.

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