Very Late-Onset Systemic Lupus Erythematosus as Unusual Cause of Reversible Functional and Cognitive Impairments in an Octogenarian Patient
  • Stephanie de Montjoye
    Rheumatology Department, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
  • Benoit Boland
    Geriatric Medicine Department, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
  • Jacqueline Van Raemdonck
    Geriatric Medicine Department, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
  • Frederic Houssiau
    Rheumatology Department, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

Keywords

Late-onset systemic lupus erythematosus, cognitive impairment, functional decline

Abstract

While functional decline is a common syndrome in geriatric medicine, the diagnosis of the underlying disease can be complex. We present a case of very late-onset systemic lupus erythematosus with fever, arthritis, lymphadenopathy, sicca syndrome, pleurisy, renal impairment and reversible functional and cognitive impairments. Prompt improvement was observed on prednisolone and hydroxychloroquine.

VIEW THE ENTIRE ARTICLE

References

  • Stojan G, Petri M. Epidemiology of systemic lupus erythematosus: an update. Curr Opin Rheumatol 2018;30(2):144–150.

  • Arnaud L, Mathian A, Boddaert J, Amoura Z. Late-onset systemic lupus erythematosus. Drugs Aging 2012;29(3):181–189.

  • das Chagas Medeiros MM, Bezzera MC, Braga FN, da Justa Feijao MR, Gois AC, Rebouças VC, et al. Clinical and immunological aspects and outcome of a Brazilian cohort of 414 patients with systemic lupus erythematosus (SLE): comparison between childhood-onset, adult-onset, and late-onset SLE. Lupus 2016;25(4):355–363.

  • Cartella S, Cavazzana I, Ceribelli A, Inverardi F, Tincani A, Franceschini F. Evaluation of mortality, disease activity, treatment, clinical and immunological features of adult and late onset systemic Lupus erythematosus. Autoimmunity 2013;46(6):363–368.

  • Lahaye C, Tatar Z, Dubost J, Soubrier M. Overview of biologic treatments in the elderly. Joint Bone Spine 2015;82(3):154–160.
  • Views: 800
    HTML downloads: 141
    PDF downloads: 630


    Published: 2020-05-07
    Issue: 2020: Vol 7 No 8 (view)


    How to cite:
    1.
    de Montjoye S, Boland B, Van Raemdonck J, Houssiau F. Very Late-Onset Systemic Lupus Erythematosus as Unusual Cause of Reversible Functional and Cognitive Impairments in an Octogenarian Patient. EJCRIM 2020;7 doi:10.12890/2020_001570.

    Similar Articles

    You may also start an advanced similarity search for this article.