Cervical Lymphadenopathy in Two Young Women The Same Rare Diagnosis with Different Presentations
  • Sonia Canadas
    Medicine Department, Internal Medicine Service, Hospital Sousa Martins, Guarda, Portugal
  • Rita Fernandes
    Medicine Department, Internal Medicine Service, Hospital Sousa Martins, Guarda, Portugal
  • Mónica Santos
    Hematology Service, Centro Hospitalar Tondela-Viseu, Viseu, Portugal
  • Ana Vera-Cruz
    Medicine Department, Internal Medicine Service, Hospital Distrital de Santarém, Santarém, Portugal
  • Ana Teresa Moreira
    Medicine Department, Internal Medicine Service, Hospital Sousa Martins, Guarda, Portugal

Keywords

Kikuchi-Fujimoto disease, histiocytic necrotizing lymphadenitis, cervical lymphadenopathy, systemic lupus erythematosus, corticosteroids

Abstract

Kikuchi-Fujimoto disease (KFD) is a rare, benign and usually self-limiting disorder that more often affects young women, which is characterized by cervical lymphadenopathy and fever. Clinical presentation may be indistinguishable from other diseases, and its inclusion in the differential diagnosis of lymphoproliferative, infective and autoimmune diseases is essential. An association with systemic lupus erythematosus is acknowledged. We present 2 different cases of 2 young women with KFD; the first case highlights the classic diagnostic features of this rare entity, and the second, the findings when KFD occurs in association with systemic lupus erythematosus.

VIEW THE ENTIRE ARTICLE

References

  • Bosch X, Guilabert A. Kikuchi-Fujimoto disease. Orphanet J Rare Dis 2006; 1:18.

  • Melikoglu MA, Melikoglu M. The clinical importance of lymphadenopathy in systemic lupus erythematosus. Acta Reumatol Port 2008;33:402–406.

  • Bosch X, Guilabert A, Miquel R, Campo E. Enigmatic Kikuchi-Fujimoto disease. Am J Clin Pathol 2004;122:141–152.

  • Deaver D, Horna P, Cualing H, Sokol L. Pathogenesis, diagnosis and management of Kikuchi-Fujimoto disease. Cancer Control 2014;21:313–321.

  • Antunes I, Botella A, Marques F, Araújo I, Abreu A, Cardiga R, et al. Dilemas de diagnóstico de linfadenite necrotizante (Doença de Kikuchi-Fujimoto). Acta Med Port 2011;24:681–684.

  • Jiang M, Pu J, Shen XD, He B. Prednisone induced two-way myocardial development in a patient with systemic lupus erythematosus. BMJ Case Rep 2014;2014:bcr2013203046.

    • Views: 761
    HTML downloads: 98
    PDF downloads: 397

    Published: 2020-03-10
    Issue: 2020: Vol 7 No 4 (view)

    How to cite:
    1.
    Canadas S, Fernandes R, Santos M, Vera-Cruz A, Moreira AT. Cervical Lymphadenopathy in Two Young Women The Same Rare Diagnosis with Different Presentations. EJCRIM 2020;7 doi:10.12890/2020_001516.