Persistent Facial Oedema and Erythema in a Woman, An Uncommon Manifestation of Chronic Cutaneous Lupus Erythematosus

  • Mónica García-Arpa Department of Dermatology, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
  • María Rodríguez-Vázquez Department of Dermatology, Hospital General Universitario de Albacte, Albacete, Spain
  • David Bellido-Pastrana Department of Internal Medicine, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
  • Natalia Villasanti-Rivas Department of Pathology, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
  • Marcos Carmona-Rodríguez Department of Dermatology, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain

Keywords

Chronic cutaneous lupus erythematosus, erythema, oedema, face

Abstract

Manifestations of chronic cutaneous lupus erythematosus are variable. Periorbital and facial swelling occurs in dermatomyositis and systemic lupus, but it has been rarely reported as a manifestation of exclusively cutaneous lupus. A 48-year-old woman presented with a 16-year history of asymptomatic, bilateral swelling and erythema of her face with marked worsening after sun exposure. No systemic symptoms were associated. A complete evaluation did not reveal other findings. Cutaneous biopsy showed features of lupus erythematosus. She was treated with photoprotection, topical tacrolimus, hydroxychloroquine and azathioprine with a partial response. Facial swelling with erythema represents quite an unusual manifestation of chronic cutaneous lupus erythematosus. Dermatomyositis, systemic lupus and Morbihan disease are the main differential diagnoses.

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References

  • Wu MY, Wang CH, Ng CY, Kuo TT, Chang YC, Yang CH, et al. Periorbital erythema and swelling as a presenting sign of lupus erythematosus in tertiary referral centers and literature review. Lupus 2018;27:1828–1837.

  • Silva LL, Romiti R, Nico MM. Persistent eyelid edema and erythema as manifestation of lupus erythematosus: a series of six cases. J Dtsch Dermatol Ges 2015;13:917–920.

  • Cyran S, Douglass MC, Silverstein JL. Chronic cutaneous lupus erythematosus presenting as periorbital edema and erythema. J Am Acad Dermatol 1992;26:334–338.

  • Ghaninejad H, Kavusi S, Safar F, Asgari M, Naraghi ZS. Persistent periorbital edema as a sole manifestation of cutaneous lupus erythematosus: report of two cases. Dermatol Online J 2006;12:14.

  • Serarslan G, Atik E, Sarikaya G. Periorbital edema and erythema: an unusual localization of DLE in a patient with psoriasis. J Dermatol 2011;38:486–488.
  • Published: 2020-02-12

    Issue: Vol 7 No 3 (view)

    Section: Articles

    How to cite:
    García-Arpa, M., Rodríguez-Vázquez, M., Bellido-Pastrana, D., Villasanti-Rivas, N., & Carmona-Rodríguez, M. (2020). Persistent Facial Oedema and Erythema in a Woman, An Uncommon Manifestation of Chronic Cutaneous Lupus Erythematosus. European Journal of Case Reports in Internal Medicine, 7(3). https://doi.org/https://doi.org/10.12890/2020_001462