A Rare Case of Primary Pulmonary Anaplastic Large Cell Lymphoma

  • Joana Carvalho Pulmonology Department, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal
  • Diogo Paixão Marques Internal Medicine Department, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal
  • Inês Oliveira Pulmonology Department, Hospital Egas Moniz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal
  • Cláudia Claudino Haematology Department, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal

Keywords

Anaplastic large cell lymphoma, ALK positive, primary lung lymphoma, lung neoplasm

Abstract

Non-Hodgkin lymphomas are rare causes of primary lung neoplasms and most are B-cell in origin. Anaplastic large cell lymphoma is an exceedingly rare type of primary pulmonary lymphoma, with an aggressive clinical course.
We present the case of an 85-year old male patient who attended our Emergency Department complaining of respiratory and constitutional symptoms, and who was found to have a bronchial mass causing subtotal atelectasis of the left lung. Histological examination showed an anaplastic large cell lymphoma and further investigation revealed that it was limited to the lung. To our knowledge, very few similar cases have been reported in the literature.

References

  • Ende E, Kauffman T, Munoz P, Martinez-Jiménez S. Primary pulmonary anaplastic large cell lymphoma: a rare malignancy and rare cause of the luftsichel sign. Case Rep Radiol 2018; article ID 8574642.

  • Han S, Maeng Y, Kim Y, Jo J, Kwon J, Kim W, et al. Primary anaplastic large cell lymphoma of the lung presenting with acute atelectasis. Thorac Cancer 2014;5(1):78–81.

  • Zhao Q, Liu Y, Chen H, Zhang Y, Du Z, Wang J, et al. Successful chemo-radiotherapy for primary anaplastic large cell lymphoma of the lung: a case report and literature review. Am J Case Rep/em> 2016;17:70–75.

  • Ferreri A, Govi S, Pileri S, Savage K. Anaplastic large cell lymphoma, ALK-positive. Crit Rev Oncol Hematol 2012;82(2012):293–302.

  • Kinney M, Higgins R, Medina E. Anaplastic large cell lymphoma – twenty-five years of discovery. Arch Pathol Lab Med 2011;135:19–43.
  • Published: 2019-09-09

    Issue: LATEST ONLINE (view)

    Section: Articles

    How to cite:
    Carvalho, J., Paixão Marques, D., Oliveira, I., & Claudino, C. (2019). A Rare Case of Primary Pulmonary Anaplastic Large Cell Lymphoma. European Journal of Case Reports in Internal Medicine, 2. https://doi.org/https://doi.org/10.12890/2019_001249