Hypercalcemia and Extensive Chest Metastasis of Vulvar Squamous Cell Carcinoma

  • Ernestina Natália Mota Serviço de Medicina 2, Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon, Portugal
  • Isabel Paulos Mesquita Serviço de Medicina 2, Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon, Portugal
  • Carlos Pires Serviço de Medicina 2, Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon, Portugal
  • Rui M.M. Victorino Serviço de Medicina, Hospital Santa Maria, Faculdade de Medicina de Lisboa, Centro Hospitalar Lisbona Norte, Lisbon, Portugal

Keywords

Squamous cell carcinoma of the vulva, paraneoplastic hypercalcemia, pulmonary metastasis of vulvar squamous cell carcinoma

Abstract

A 73-year-old woman with a diagnosis of vulvar carcinoma submitted to curative surgery 5 years previously, presented to the emergency department with prostration and vulvar haemorrhage. Although the gynaecological examination was unremarkable, she had a mass in the left chest wall and hypercalcemia. A CT scan of the thorax revealed a voluminous left hemithorax mass invading the mediastinum, lung, pleura and chest wall. Ultrasound-guided biopsy of the mass showed infiltration by a well-differentiated keratinizing squamous cell carcinoma (SCC). This case report describes an extremely rare metastatic pattern in vulvar SCC concomitant with paraneoplastic hypercalcemia.

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  • Published: 2019-09-02

    Issue: LATEST ONLINE (view)

    Section: Articles

    How to cite:
    Mota, E., Mesquita, I., Pires, C., & Victorino, R. (2019). Hypercalcemia and Extensive Chest Metastasis of Vulvar Squamous Cell Carcinoma. European Journal of Case Reports in Internal Medicine, 2. https://doi.org/https://doi.org/10.12890/2019_001218