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Light-Chain Deposition Disease with Prominent Hepatic Involvement
Ana Vaz Cristino, Carmen Tavares Pais, Renata Violante Silva, Paulo Carrola
http://dx.doi.org/10.12890/2017_000545
European Journal of Case Reports in Internal Medicine - © EFIM

ABSTRACT

Light-chain deposition disease (LCDD) is a rare monoclonal gammopathy that involves the deposition of light chains (LC) in multiple organs, leading to progressive dysfunction. The kidney is usually the most affected organ and responsible for the initial clinical manifestations. We present the case of a patient with LCDD with prominent liver involvement (marked cholestasis, hepatomegaly and portal hypertension) but with no evidence of coexisting lymphoproliferative disorder.

KEYWORDS

Light-chain deposition; monoclonal; plasma cell

References
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