Reversible 'unstable' abdominal angina caused by ruptured plaque of the superior mesenteric artery: clinical and radiological correlations
  • Shaul Yaari
    Department of Medicine, Hadassah Hebrew University Hospital, Mount Scopus, Jerusalem, Israel
  • Nurith Hiller
    Department of Radiology, Hadassah Hebrew University Hospital, Mount Scopus, Jerusalem, Israel
  • Yacov Samet
    Department of Vascular Surgery, Shaare Zedek Medical Center, Jerusalem, Israel
  • Samuel Noam Heyman
    Department of Medicine, Hadassah Hebrew University Hospital, Mount Scopus, Jerusalem, Israel

Keywords

Mesenteric ischemia, abdominal angina, atherosclerosis, unstable angina, superior mesenteric artery, atheromatous plaque

Abstract

Unstable angina, characteristic of coronary artery disease, is caused by in-situ clot formation complicating ruptured atheromatous plaque. Abdominal angina, however, usually reflects chronic mesenteric ischaemia, caused by multi-vessel stable plaques involving mesenteric arteries. Herein, we describe a patient with new-onset abdominal pain caused by a ruptured atheromatous plaque at the superior mesenteric root. The diagnosis was based on an evident reversible epigastric bruit and high-degree eccentric stenosis caused by a non-calcified atheroma. Symptoms and bruit resolved within 3 weeks on aspirin and statins with regression of the stenotic lesion. Although the condition is likely common, this is the first clear-cut report compatible with 'unstable' abdominal angina, resolved by conservative treatment.

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References

  • Derrick JR, Pollard HS, Moore RM. The pattern of arteriosclerotic narrowing of the celiac and superior mesenteric arteries. Ann Surg 1959;149:684–689.
  • Heyman SN, Leibowitz D, Mor-Yosef Levi I, Liberman A, Eisenkraft A, Alcalai R, et al. Hypoxia-adaptive response and remote ischemia preconditioning: a new hypoxia inducible factors era in clinical medicine. Acta Physiol (Oxf) 2016;216:395–406.
  • Wong YL, Lautenschläger I, Hummitzsch L, Zitta K, Cossais F, Wedel T, et al. Effects of different ischemic preconditioning strategies on physiological and cellular mechanisms of intestinal ischemia/reperfusion injury: implication from an isolated perfused rat small intestine model. PLoS One 2021;16:e0256957.
  • Sardar P, White CJ. Chronic mesenteric ischemia: diagnosis and management. Prog Cardiovasc Dis 2021;65:71–75.
  • van Petersen AS, Kolkman JJ, Meerwaldt R, Huisman AB, van der Palen J, Zeebregts CJ, et al. Mesenteric stenosis, collaterals, and compensatory blood flow. J Vasc Surg 2014;60:111–119.
  • Acosta S. Epidemiology of mesenteric vascular disease: clinical implications. Semin Vasc Surg 2010;23:4–8.
  • Berman LG, Russo FR. Abdominal angina. N Engl J Med 1950;242:611–613.
  • Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes. N Engl J Med 1992;326:310–318.
  • Sherman CT, Litvack F, Grundfest W, Lee M, Hickey A, Chaux A, et al. Coronary angioscopy in patients with unstable angina pectoris. N Engl J Med 1986;315:913–919.
  • Wood P. Acute and subacute coronary insufficiency. Br Med J 1961;1(5242):1779–1782.
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    Published: 2023-04-06
    Issue: 2023: Vol 10 No 4 (view)


    How to cite:
    1.
    Yaari S, Hiller N, Samet Y, Heyman SN. Reversible ’unstable’ abdominal angina caused by ruptured plaque of the superior mesenteric artery: clinical and radiological correlations. EJCRIM 2023;10 doi:10.12890/2023_003766.

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