Successful Conservative Treatment of a Complicated Aortic Thrombus in a Woman with Factor V Leiden Mutation
  • Elise Frebutte
    Internal Medicine Department, CHR Haute Senne, Soignies, Belgium
  • Myriam Bibombe
    Internal Medicine Department, CHR Haute Senne, Soignies, Belgium
  • Arthur Dumont
    Internal Medicine Department, CHR Haute Senne, Soignies, Belgium
  • Maxime Haxhe
    Radiology Department, CHR Haute Senne, Soignies, Belgium
  • Pascal Reper
    Critical Care Department, CHR Haute Senne, Soignies, Belgium; Critical Care Department, CHU UCL Namur, Yvoir, Belgium; ederal Health Ministry, Brussels, Belgium

Keywords

Aortic thrombus, factor V Leiden, anticoagulation, Embolism

Abstract

Thrombus in the aortic trunk is a rare complication. We report the case of a 63-year-old patient with a factor V Leiden mutation in whom an aortic arch thrombus was discovered accidentally. Conservative treatment was initiated with therapeutic anticoagulation with low-molecular-weight heparin leading to complete thrombus lysis after 3 months but associated shortly after anticoagulation initiation with a large splenic and limited renal infarctions.

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References

  • Li HD, Sun TC. Bowel ischemia caused by a giant thrombus in the ascending aorta. A case report. Vascular 2015;23:641–644.
  • Tsilimparis N, Hanack U, Pisimisis G. Thrombus in the non-aneurysmal, non-atherosclerotic descending thoracic aorta: an unusual source of arterial embolism. Eur J Vasc Endovasc Surg 2011;41:450–457.
  • Choukroun EM, Labrousse LM, Madonna FP. Mobile thrombus of the thoracic aorta: diagnosis and treatment in 9 cases. Ann Vasc Surg 2002;16:714–722.
  • Pagni S, Trivedi J, Ganzel BL. Thoracic aortic mobile thrombus: is there a role for early surgical intervention? Ann Thorac Surg 2011;91:1875–1881.
  • Deschka H, Erler S, Machner M. Surgery of the ascending aorta, root remodelling and aortic arch surgery with circulatory arrest through partial upper sternotomy: results of 50 consecutive cases. Eur J Cardiothorac Surg 2013;43:580–584.
  • Roselli EE, Idrees J, Greenberg RK. Endovascular stent grafting for ascending aorta repair in high-risk patients. J Thorac Cardiovasc Surg 2015;149:144–151.
  • Mahnken AH, Hoffman A, Autschbach R. Bare metal stenting for endovascular exclusion of aortic arch thrombi. Cardiovasc Intervent Radiol 2013;36:1127–1131.
  • Rancic Z, Pfammatter T, Lachat M. Floating aortic arch thrombus involving the supraaortic trunks: successful treatment with supra-aortic debranching and antegrade endograft implantation. J Vasc Surg 2009;50:1177–1180.
  • Melissano G, Tshomba Y, Bertoglio L. Analysis of stroke after TEVAR involving the aortic arch. Eur J Vasc Endovasc Surg 2012;43:269–275.
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    Published: 2021-06-07
    Issue: 2021: Vol 8 No 6 (view)


    How to cite:
    1.
    Frebutte E, Bibombe M, Dumont A, Haxhe M, Reper P. Successful Conservative Treatment of a Complicated Aortic Thrombus in a Woman with Factor V Leiden Mutation. EJCRIM 2021;8 doi:10.12890/2021_002641.

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