HIV Infection Presenting as Haemophagocytic Syndrome
  • Sara Vieira Silva
    Internal Medicine Department, Santo António Hospital, Porto Hospital Centre, Porto
  • Margarida França
    Internal Medicine Department, Santo António Hospital, Porto Hospital Centre, Porto


The authors describe a case of a 48-year-old man who presented with four weeks of fever, generalized malaise, weight loss, right upper quadrant abdominal pain and hepatosplenomegaly. He evolved with pancytopenia, bone marrow haemophagocytosis and hyperferritinaemia. Recent diagnosis of HIV infection, with the exclusion of other plausible causes, prompted the diagnosis of haemophagocytic syndrome (HPS) secondary to HIV. Despite intensive care support and initiation of antiretroviral therapy, the patient died. HPS diagnosis secondary to HIV alone demands the exclusion of all the other secondary causes. The best approach includes early diagnosis and specific treatment of the associated cause, whenever possible.



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    Published: 2014-09-12
    Issue: Vol. 1 (2014) (view)

    How to cite:
    Vieira Silva S, França M. HIV Infection Presenting as Haemophagocytic Syndrome. EJCRIM 2014;1 doi:10.12890/2014_000099.