Not So Incidental: Pheochromocytoma in an Adult with Unrepaired Cyanotic Heart Disease

  • Nikesh Adunuri Department of Internal Medicine, University of Western Ontario, London, Canada
  • Marko Mrkobrada Department of Internal Medicine, University of Western Ontario, London, Canada

Keywords

Pheochromocytoma, cyanotic heart disease

Abstract

Pheochromocytoma, a rare neuroendocrine tumour, is often encountered in the general internal medicine clinic as an adrenal incidentaloma. Even rarer is its presence in adult cyanotic heart disease, although there are a few documented reports of this association in various paediatric populations, with chronic hypoxia being the likely driving force. Here we present the case of a 38-year-old adult with unrepaired complex cyanotic congenital heart disease with biochemically proven pheochromocytoma presenting as an adrenal incidentaloma to a general internal medicine clinic.

References

  • Yamamoto K, Namba N, Kubota T, et al. Pheochromocytoma complicated by cyanotic congenital heart disease: a case report. Clin Pediatr Endocrinol 2016;25:59–65.

  • Zhao B, Zhou Y, Zhao Y, et al. Co-occurrence of pheochromocytoma-paraganglioma and cyanotic congenital heart disease: a case report and literature review. Front Endocrinol (Lausanne) 2018;9:1–6.

  • Opotowsky AR, Moko LE, Ginns J, et al. Pheochromocytoma and paraganglioma in cyanotic congenital heart disease. J Clin Endocrinol Metab 2015;100:1325–1334.

  • de la Monte SM, Hutchins GM, Moore GW. Peripheral neuroblastic tumors and congenital heart disease. Possible role of hypoxic states in tumor induction. Am J Pediatr Hematol Oncol 1985;7:109–116.

  • Cheung YW, Spevack DM. Single left ventricle and pheochromocytoma. Congenit Heart Dis 2008;3:355–358.

  • Latendresse TR, Goldin AB, Jonmarker C. Anesthesia for pheochromocytoma resection in a child with Fontan circulation. Can J Anesth 2011;58:642–645.

  • Suffredini G, Diaz-Rodriguez N, Chakravarthy K, et al. Anesthetic management of pheochromocytoma resection in adults with single ventricle physiology. Cureus 2017;9:e1928.
  • Published: 2018-10-09

    Issue: LATEST ONLINE (view)

    Section: Articles

    How to cite:
    Adunuri, N., & Mrkobrada, M. (2018). Not So Incidental: Pheochromocytoma in an Adult with Unrepaired Cyanotic Heart Disease. European Journal of Case Reports in Internal Medicine, 2. https://doi.org/https://doi.org/10.12890/2018_000959