Serotonin Surge: Intravenous Escitalopram as a Rare Cause of Drug-Induced Aplastic Anaemia

  • Murtaza Hussain Department of Internal Medicine, Michigan State University at Hurley Medical Center, Flint, MI, USA https://orcid.org/0000-0003-4641-800X
  • Katherine Boyer Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA https://orcid.org/0000-0001-5947-4057
  • Anoosha Ponnapalli Department of Internal Medicine, Michigan State University at Hurley Medical Center, Flint, MI, USA
  • Dominic Awuah Department of Internal Medicine, Michigan State University at Hurley Medical Center, Flint, MI, USA
  • Sina Khaneki Internal Medicine Physician at Kaiser Permanente, Lincoln, CA, USA
  • Smit Deliwala Department of Internal Medicine, Michigan State University at Hurley Medical Center, Flint, MI, USA https://orcid.org/0000-0001-5239-9533
  • Ghassan Bachuwa Department of Internal Medicine, Michigan State University at Hurley Medical Center, Flint, MI, USA https://orcid.org/0000-0001-6763-4508
DOI: https://doi.org/10.12890/2022_003228

Keywords

Intravenous escitalopram, drug-induced aplastic anaemia, hypoproliferative pancytopenia

Abstract

Escitalopram is a commonly prescribed medication that has infrequently been implicated in drug-induced thrombocytopenia (DITP) but has never been associated with aplastic anaemia in the literature. We present an extremely rare case of hypoproliferative pancytopenia due to self-administered intravenous (IV) injection of escitalopram. The crux of this case is the unusual trilineage cytopenia. Our patient was managed with steroids and supportive care with subsequent clinical and blood count recovery. This case sheds light on this uncommon but important association.

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    • Published: 2022-03-04

    Issue: 2022: Vol 9 No 3 (view)

    Section: Articles

    How to cite:
    1.
    Hussain M, Boyer K, Ponnapalli A, Awuah D, Khaneki S, Deliwala S, Bachuwa G. Serotonin Surge: Intravenous Escitalopram as a Rare Cause of Drug-Induced Aplastic Anaemia. EJCRIM 2022;9 doi:10.12890/2022_003228.

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