Cardiac Sodium Channel Blockade Due to Antiepileptic Drug Combination

  • Ossama Maadarani Internal Medicine Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Zouheir Bitar nternal Medicine Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Abdelaziz Ashkanani Internal Medicine Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Mahmoud Elzoueiry nternal Medicine Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Mohamad Elhabibi Internal Medicine Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Mohammad Gohar Internal Medicine Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Mohamad Almuwaiziri Nursing Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Sania Soeb nternal Medicine Department, Al Salam Hospital, Kuwait
  • Jadan Alsaddah Department of Cardiology, Chest Diseases Hospital, Kuwait

Keywords

Sodium channel blockers, lacosamide, electrocardiogram

Abstract

Drugs that inhibit voltage-dependent sodium channels are commonly used to treat epilepsy. Old and novel antiepileptic drugs are used either as monotherapy or in combination to control epilepsy. For a long time, carbamazepine has been used as the first choice for the treatment of simple and complex partial seizures. In the USA, lacosamide was approved in October 2008 as an adjunctive treatment for partial-onset seizures. We describe the effect of two sodium channel blockers on the heart of a patient with epilepsy.

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  • Published: 2021-10-04

    Issue: 2021: Vol 8 No 10 (view)

    Section: Articles

    How to cite:
    1.
    Maadarani O, Bitar Z, Ashkanani A, Elzoueiry M, Elhabibi M, Gohar M, Almuwaiziri M, Soeb S, Alsaddah J. Cardiac Sodium Channel Blockade Due to Antiepileptic Drug Combination. EJCRIM 2021;8 doi:10.12890/2021_002839.