Cardiac Sodium Channel Blockade Due to Antiepileptic Drug Combination
  • Ossama Maadarani
    Internal Medicine Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Zouheir Bitar
    nternal Medicine Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Abdelaziz Ashkanani
    Internal Medicine Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Mahmoud Elzoueiry
    nternal Medicine Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Mohamad Elhabibi
    Internal Medicine Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Mohammad Gohar
    Internal Medicine Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Mohamad Almuwaiziri
    Nursing Department, Ahmadi Hospital, Kuwait Oil Company, Al Ahmadi, Kuwait
  • Sania Soeb
    nternal Medicine Department, Al Salam Hospital, Kuwait
  • Jadan Alsaddah
    Department of Cardiology, Chest Diseases Hospital, Kuwait

Keywords

Sodium channel blockers, lacosamide, electrocardiogram

Abstract

Drugs that inhibit voltage-dependent sodium channels are commonly used to treat epilepsy. Old and novel antiepileptic drugs are used either as monotherapy or in combination to control epilepsy. For a long time, carbamazepine has been used as the first choice for the treatment of simple and complex partial seizures. In the USA, lacosamide was approved in October 2008 as an adjunctive treatment for partial-onset seizures. We describe the effect of two sodium channel blockers on the heart of a patient with epilepsy.

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    Published: 2021-10-04
    Issue: 2021: Vol 8 No 10 (view)


    How to cite:
    1.
    Maadarani O, Bitar Z, Ashkanani A, Elzoueiry M, Elhabibi M, Gohar M, Almuwaiziri M, Soeb S, Alsaddah J. Cardiac Sodium Channel Blockade Due to Antiepileptic Drug Combination. EJCRIM 2021;8 doi:10.12890/2021_002839.

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