Blood culture-negative endocarditis caused by Tropheryma whipplei: a case report of Whipple’s endocarditis

  • Silke Knol Department of Cardiology, Hospital Group Twente (ZGT), Almelo and Hengelo, The Netherlands
  • Rogier L Nijhuis Department of Cardiology, Hospital Group Twente (ZGT), Almelo and Hengelo, The Netherlands
  • Felix Geeraedts Laboratory Microbiology Twente Achterhoek (LabMicTA), Hengelo, The Netherlands
  • Gerard Linssen Department of Cardiology, Hospital Group Twente (ZGT), Almelo and Hengelo, The Netherlands

Keywords

Whipple’s endocarditis, Tropheryma whipplei, blood culture-negative endocarditis

Abstract

Case description: A 67-year-old man was admitted with progressive heart failure, due to blood culture-negative endocarditis of the aortic valve. In early course, urgent aortic valve replacement was needed. A polymerase chain reaction test (PCR) on samples of the explanted aortic valve revealed Tropheryma whipplei. He received ceftriaxone, followed by long-term co-trimoxazole. Recent arthralgia may have been a diagnostic clue.

Conclusion: Whipple’s endocarditis should be assessed in patients with arthralgia and blood culture-negative endocarditis (BCNIE).

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References

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  • Published: 2021-05-19

    Issue: 2021: Vol 8 No 5 (view)

    Section: Articles

    How to cite:
    1.
    Knol S, Nijhuis RL, Geeraedts F, Linssen G. Blood culture-negative endocarditis caused by Tropheryma whipplei: a case report of Whipple’s endocarditis. EJCRIM 2021;8 doi:10.12890/2021_002596.