Erythema Nodosum Revealing Metastatic Lung Cancer

  • Anis Mzabi Internal Medicine Department, Sahloul University Hospital, Sousse, Tunisia
  • Wafa Benzarti Pneumology Department, Farhat Hached University Hospital, Sousse, Tunisia
  • Wiem Romdhane Internal Medicine Department, Sahloul University Hospital, Sousse, Tunisia
  • Wafa Baya Internal Medicine Department, Sahloul University Hospital, Sousse, Tunisia
  • Sana Aissa Pneumology Department, Farhat Hached University Hospital, Sousse, Tunisia
  • Imen Gargouri Pneumology Department, Farhat Hached University Hospital, Sousse, Tunisia
  • Chedia Laouani Internal Medicine Department, Sahloul University Hospital, Sousse, Tunisia

Keywords

Erythema nodosum, paraneoplastic syndrome, lung cancer

Abstract

Erythema nodosum (EN) is an inflammatory condition of the subcutaneous fat and has been reported in patients with haematological malignancies (lymphomas) or solid tumours. Lung cancer is the most common cause of paraneoplastic syndrome. We report a case of EN occurring as a paraneoplastic disease.
A 48-year-old Tunisian woman, a non-smoker with no relevant medical history, presented with painful, erythematous, firm nodules on her legs with ankle swelling. The patient did not report any other symptoms. There were no abnormalities on examination except for moderate fever. An extensive infectious and immunological investigation was negative. Antistreptolysin antibodies were undetectable. Chest radiography showed a focal opacity in the right lung and a CT scan revealed a mass in the lower right pulmonary lobe with hilar and mediastinal lymphadenopathies, a nodule in the right adrenal gland, condensation in the iliac bone and multiple bilateral nodular cerebral expansive processes. Bronchial biopsies revealed a primitive and moderately differentiated adenocarcinoma. No argument for tuberculosis or sarcoidosis was found.

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  • Published: 2021-07-21

    Issue: 2021: LATEST ONLINE (view)

    Section: Articles

    How to cite:
    1.
    Mzabi A, Benzarti W, Romdhane W, Baya W, Aissa S, Gargouri I, Laouani C. Erythema Nodosum Revealing Metastatic Lung Cancer. EJCRIM 2021;2 doi:10.12890/2021_002539.

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