Primary Malignant Mesothelioma of the Liver: Case Report and Review of the Literature
  • Subash Ghimire
    Guthrie Robert Packer Hospital, Sayre, PA, USA
  • Nilisha Regmi
    Jinnah Sindh Medical College, Karachi, Pakistan
  • Tsujung Yang
    Guthrie Robert Packer Hospital, Sayre, PA, USA
  • Harshil Shah
    Guthrie Robert Packer Hospital, Sayre, PA, USA
  • Ukorn Srivatana
    Guthrie Robert Packer Hospital, Sayre, PA, USA
  • Ashit Sarker
    Guthrie Robert Packer Hospital, Sayre, PA, USA
  • Hafiz Khan
    Guthrie Robert Packer Hospital, Sayre, PA, USA

Keywords

Primary malignant mesothelioma, liver cancer, asbestosis

Abstract

Introduction: Primary malignant mesothelioma of the liver is an extremely rare cancer, with only 16 cases reported in the literature so far. Diagnosis is challenging due to morphological similarity with common liver cancers and the extreme rarity of the condition.

Case description: We present the case of a 70-year-old man who was found to have an incidental liver mass which was diagnosed as primary malignant mesothelioma of the liver.

Conclusion: Our report describes the presentation of this rare liver malignancy and the challenges associated with diagnosis and treatment.

 

VIEW THE ENTIRE ARTICLE

References

  • Sekido Y. Molecular pathogenesis of malignant mesothelioma. Carcinogenesis 2013;34(7):1413–9.
  • Ghimire S, Yang T, Shah H, Srivatana U, Sarker A. Primary malignant mesothelioma of liver: a rare liver tumor. Am J Gastroenterol 2019;114(1):S1257–S1257.
  • Kim J, Bhagwandin S, Labow DM. Malignant peritoneal mesothelioma: a review. Ann Transl Med 2017;5(11):236. doi: 10.21037/atm.2017.03.96.
  • Ismael H, Cox S. Primary intrahepatic mesotheliomas: A case presentation and literature review. Int J Surg Case Rep 2018;47:1–6.
  • Imura J, Ichikawa K, Takeda J, Iwasaki Y, Tomita S, Kubota K, et al. Localized malignant mesothelioma of the epithelial type occurring as a primary hepatic neoplasm: A case report with review of the literature. APMIS 2002;110(11):789–94.
  • Sasaki M, Araki I, Yasui T, Kinoshita M, Itatsu K, Nojima T, et al. Primary localized malignant biphasic mesothelioma of the liver in a patient with asbestosis. World J Gastroenterol 2009;15(5):615–21.
  • Kim H, Damjanov I. Localized fibrous mesothelioma of the liver. Report of a giant tumor studied by light and electron microscopy. Cancer 1983;52(9):1662–5.
  • Gütgemann I, Standop J, Fischer HP. Primary intrahepatic malignant mesothelioma of epithelioid type. Virchows Arch 2006;448(5):655–8.
  • Haji Ali R, Khalife M, El Nounou G, Zuhri Yafi R, Nassar H, Aidibe Z, et al. Giant primary malignant mesothelioma of the liver: a case report. Int J Surg Case Rep 2017;30:58–61.
  • Leonardou P, Semelka RC, Kanematsu M, Braga L, Woosley JT. Primary malignant mesothelioma of the liver: MR imaging findings. Magn Reson Imaging 2003;21(9):1091–3.
  • Di Blasi A, Boscaino A, De Dominicis G, Marsilia GM, D’Antonio A, Nappi O. Multicystic mesothelioma of the liver with secondary involvement of peritoneum and inguinal region. Int J Surg Pathol 2004;12(1):87–91.
  • Kim DS, Lee SG, Jun SY, Kyoung WK, Ha TY, Kim KK. Primary malignant mesothelioma developed in liver. Hepatogastroenterology 2008; 55:1081-1084.
  • Inagaki N, Kibata K, Tamaki T, Shimizu T, Nomura S. Primary intrahepatic malignant mesothelioma with multiple lymphadenopathies due to non-tuberculous mycobacteria: A case report and review of the literature. Oncol Lett 2013; 6(3):676–80.
  • Dong A, Dong H, Zuo C. Multiple primary hepatic malignant mesotheliomas mimicking cystadenocarcinomas on enhanced CT and FDG PET/CT. Clin Nucl Med 2014;39(7):619–22.
  • Perysinakis I, Nixon AM, Spyridakis I, Kakiopoulos G, Zorzos C, Margaris I. Primary intrahepatic malignant epithelioid mesothelioma. Int J Surg Case Rep 2014;5(12):1098–101.
  • Serter A, Buyukpinarbasili N, Karatepe O, Kocakoc E. An unusual liver mass: primary malignant mesothelioma of the liver: CT and MRI findings and literature review. Jpn J Radiol 2014;33(2):102–6.
  • Minami K, Okumura H, Hiwatashi K, Matsukita S, Setoyama T, Minamimagari K, et al. Multiple malignant epithelioid mesotheliomas of the liver and greater omentum: a case report and review of the literature. Surg Case Reports 2017;3(1).
  • Wong S, Gargi D, Cha C, Klimstra D, Jain D. Primary mesothelioma of the iver: a case report. Ajsp Rev Reports 2019;24(4).
  • Views: 818
    HTML downloads: 139
    PDF downloads: 363


    Published: 2020-12-18
    Issue: 2020: Vol 7 No 12 (view)


    How to cite:
    1.
    Ghimire S, Regmi N, Yang T, Shah H, Srivatana U, Sarker A, Khan H. Primary Malignant Mesothelioma of the Liver: Case Report and Review of the Literature. EJCRIM 2020;7 doi:10.12890/2020_002128.

    Most read articles by the same author(s)