Embolic Showering from Non-Bacterial Thrombotic Endocarditis and Adenocarcinoma of the Lung

  • Brian Cheung Saint Bernards Healthcare, Jonesboro, Arkansas, USA
  • Abhijit Shivkumar Saint Bernards Healthcare, Jonesboro, Arkansas, USA
  • Ahmed Ahmed Saint Bernards Healthcare, Jonesboro, Arkansas, USA
DOI: https://doi.org/10.12890/2020_001798

Keywords

Endocarditis, infective endocarditis, lung cancer, marantic endocarditis

Abstract

Background: Non-bacterial thrombotic endocarditis (NBTE) is a paraneoplastic phenomenon with sterile vegetations. It is associated with adenocarcinoma and can shower emboli, which can be the presenting symptom.
Case Presentation: A 44-year-old woman with adenocarcinoma of the lung presented with chest pain, left hand weakness, and ataxia due to repeated embolic showering from NBTE to the central nervous system (CNS) and spleen.
Conclusion: NBTE is a rare condition that should be on the differential diagnosis in patients with culture-negative endocarditis and a history of adenocarcinoma.

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References

  • Liu J, Frishman WH. Nonbacterial thrombotic endocarditis: pathogenesis, diagnosis, and management. Cardiol Rev 2016;24(5):244–247.

  • Bedikian A, Valdivieso M, Luna M, Bodey GP. Nonbacterial thrombotic endocarditis in cancer patients: comparison of characteristics of patients with and without concomitant disseminated intravascular coagulation. Med Pediatr Oncol 1978;4(2):149–157.

  • Baddour LM, Wilson WR, Bayer AS, Fowler VG, Tleyjeh IM, Rybak MJ, et al. Infective endocarditis in adults: diagnosis, antimicrobial therapy, and management of complications: a scientific statement for healthcare professionals from the American Heart Association. Circulation 2013;132(15):1435–1486.

  • Li JS, Sexton DJ, Mick N, Nettles R, Fowler VG, Ryan T, et al. Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis 2000;30(4):633–638.

  • Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP, Guyton RA, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2014;63(22):2438–2488.

    • Published: 2020-07-20

    Issue: Vol 7 No 10 (view)

    Section: Articles

    How to cite:
    1.
    Cheung B, Shivkumar A, Ahmed A. Embolic Showering from Non-Bacterial Thrombotic Endocarditis and Adenocarcinoma of the Lung. EJCRIM 2020;7 doi:10.12890/2020_001798.

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