Long-term Positivity to SARS-CoV-2: A Clinical Case of COVID-19 with Persistent Evidence of Infection

  • Damiano D'Ardes Internal Medicine, Department of Medicine and Science of Aging, ‘G. D'Annunzio’ University, Chieti, Italy
  • Andrea Boccatonda Ultrasound Unit, Internal Medicine, Department of Medicine and Science of Aging, ‘G. D'Annunzio’ University, Chieti, Italy
  • Ilaria Rossi Internal Medicine, Department of Medicine and Science of Aging, ‘G. D'Annunzio’ University, Chieti, Italy
  • Michela Pontolillo Infectious Diseases Unit, Department of Medicine and Science of Aging, "G. d'Annunzio" University, Chieti, Italy
  • Giulio Cocco Ultrasound Unit, Internal Medicine, Department of Medicine and Science of Aging, ‘G. D'Annunzio’ University, Chieti, Italy
  • Cosima Schiavone Ultrasound Unit, Internal Medicine, Department of Medicine and Science of Aging, ‘G. D'Annunzio’ University, Chieti, Italy
  • Francesca Santilli Internal Medicine, Department of Medicine and Science of Aging, ‘G. D'Annunzio’ University, Chieti, Italy
  • Maria Teresa Guagnano Internal Medicine, Department of Medicine and Science of Aging, ‘G. D'Annunzio’ University, Chieti, Italy
  • Marco Bucci Internal Medicine, Department of Medicine and Science of Aging, ‘G. D'Annunzio’ University, Chieti, Italy
  • Francesco Cipollone Internal Medicine, Department of Medicine and Science of Aging, ‘G. D'Annunzio’ University, Chieti, Italy

Keywords

SARS-CoV-2, COVID-19, persistent infection

Abstract

In December 2019, an outbreak of a new coronavirus (SARS-CoV-2) was reported in Hubei province in China. The disease has since spread worldwide and the World Health Organization declared it a pandemic on 11 March 2020. We describe the case of a 65-year-old woman who clinically recovered from COVID-19 but showed persistent infection with SARS-CoV-2 for 51 days.

VIEW THE ENTIRE ARTICLE

References

  • Xu K, Chen Y, Yuan J, Yi P, Ding C, Wu W, et al. Factors associated with prolonged viral RNA shedding in patients with COVID-19. Clin Infect Dis 2020 Apr 9. pii: ciaa351. doi: 10.1093/cid/ciaa351 [Epub ahead of print].

  • Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020:395;1054–1062.

  • Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 2020;382(8):727–733.

  • Sofia S, Boccatonda A, Montanari M, Spampinato M, D’ardes D, Cocco G, et al. Thoracic ultrasound and SARS-COVID-19: a pictorial essay. J Ultrasound 2020 Apr 16. doi: 10.1007/s40477-020-00458-7 [Epub ahead of print].

  • Lan L, Xu D, Ye G, Xia C, Wang S, Li Y, et al. Positive RT-PCR test results in patients recovered from COVID-19. JAMA 2020 Feb 27. doi: 10.1001/jama.2020.2783 [Epub ahead of print].

  • D’Ardes D, Boccatonda A, Schiavone C, Santilli F, Guagnano MT, Bucci M, et al. A case of coinfection with SARS-COV-2 and cytomegalovirus in the era of COVID-19. Eur J Case Rep Intern Med 2020; 7(5). https://doi.org/https://doi.org/10.12890/2020_001652.

  • Chen C, Gao G, Xu Y, Pu L, Wang Q, Wang L, et al. SARS-CoV-2–positive sputum and feces after conversion of pharyngeal samples in patients with COVID-19. Ann Intern Med 2020 Mar 30. doi: 10.7326/M20-0991 [Epub ahead of print].
  • Published: 2020-05-11

    Issue: Vol 7 No 6 (view)

    Section: Articles

    How to cite:
    D’Ardes, D., Boccatonda, A., Rossi, I., Pontolillo, M., Cocco, G., Schiavone, C., Santilli, F., Guagnano, M. T., Bucci, M., & Cipollone, F. (2020). Long-term Positivity to SARS-CoV-2: A Clinical Case of COVID-19 with Persistent Evidence of Infection. European Journal of Case Reports in Internal Medicine, 7(6). https://doi.org/10.12890/2020_001707

    Most read articles by the same author(s)