Multiple Myeloma Presenting with Distal Limb Gangrene: An Odd Case Report
  • Joana Jacinto
    Internal Medicine Department, Central Hospital of Funchal SESARAM, Funchal
  • Alexandra Malheiro
    Internal Medicine Department, Central Hospital of Funchal SESARAM, Funchal
  • Andreia Pestana
    Central Hospital of Funchal - SESARAM
  • Tiago Freitas
    Internal Medicine Department, Central Hospital of Funchal SESARAM, Funchal
  • M. Luz Brazão
    Internal Medicine Department, Central Hospital of Funchal SESARAM, Funchal

Keywords

Multiple myeloma, hyperviscosity, gangrene

Abstract

Multiple myeloma (MM) is a plasmocytic malignant proliferation of a single clone resulting in an overabundance of monoclonal immunoglobulins. MM commonly presents with bone disorders, renal failure, anaemia and hypercalcaemia. Hyperviscosity syndrome is rare, as are vaso-occlusive symptoms. The authors report a dramatic case of an 80-year-old woman admitted to the emergency department with full-blown distal gangrene. The culprit turned out to be a MM, unusually presenting with symptomatic hyperviscosity and peripheral occlusive ischaemia. This catastrophic and particularly dramatic presentation is almost unprecedented, with only a few cases reported worldwide.

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References

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    Published: 2014-12-01
    Issue: Vol. 1 (2014) (view)

    How to cite:
    1.
    Jacinto J, Malheiro A, Pestana A, Freitas T, Brazão ML. Multiple Myeloma Presenting with Distal Limb Gangrene: An Odd Case Report. EJCRIM 2014;1 doi:10.12890/2014_000167.

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