Autoimmune Hepatitis and Systemic Sclerosis: a Rare Association
KeywordsAutoimmune hepatitis, systemic sclerosis, alcoholic hepatitis
A woman in her early 40s, with a history of excessive alcohol intake, presented with purpuric, ulcerative lesions on the lower limbs. On examination, hirsutism and generalized stiffening and thickening of the skin were noted. Laboratory investigations revealed hyperbilirubinemia, hypergammaglobulinemia and positive anti-smooth muscle antibodies. Histologic examination of the skin was compatible with scleroderma. Histologic examination of the liver was suggestive of autoimmune and alcoholic hepatitis.
Issue: Vol 6 No 12 (view)