Pier Mannuccio Mannucci graduated in Medicine from the University of Milan, Italy, in 1963 and subsequently specialized in haematology, cardiology, and angiology. He completed postgraduate research training in the United Kingdom, including appointments at St Thomas' Hospital in London and the University of Oxford.
He is Emeritus Professor of Internal Medicine at the University of Milan, where he held several senior academic and clinical positions. From 1989 to 2010, he directed the Angelo Bianchi Bonomi Haemophilia and Thrombosis Centre at the Ospedale Maggiore Policlinico in Milan. He subsequently served as Scientific Director of the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico from 2010 to 2015.
His main research interests include haemophilia, von Willebrand disease, inherited thrombophilia, venous thromboembolism, and cardiovascular diseases. His more recent research has focused on the effects of environmental pollution on cardiovascular health and the challenges of polypharmacy in older patients with multiple chronic conditions.
He has authored or co-authored more than 1,200 scientific publications and has received numerous prestigious international awards for his contributions to haematology and thrombosis research. He served as President of the International Society on Thrombosis and Haemostasis (ISTH) from 1996 to 1997 and has been widely recognized for his pioneering work on the diagnosis and treatment of bleeding disorders.